Fort St. Louis. Thirteen miles southeast of Inez is located the site of Fort St. Louis. First French settlement in Texas attempted by Rene Robert Cavelier Sieur de La Salle in 1685. Devastated by the Karankawa Indians, burned by members of the Alonso De Leon Expedition in 1689. On its remains the Spaniards constructed Presidio de Nuestra Senora de la Bahia del Espirtu Santo, Marquis of Aguayo and Father Fray Agustin Patron, O.F. M. In 1722 as a protection for the mission of Nuestra Senora del Espiritu Santo de Zuniga for the civilizing and christianizing of the Indian tribes of the vicintiy moved to Mission Valley on the Guadalupe River near the present Victoria in 1726; moved finally to Santa Dorotea in Goliad near the San Antonio River in 1749. #2020