John Wallace Jr.. Laid out the present town in 1797 and named it Waynesburg in honor of General Anthony Wayne. In 1831, name changed to Waynesboro. Stone portion of the Wallace house still stands about 200 yards southeast of here. E. Main & Enterprise Sts., Waynesboro, PA by Pennsylvania Historical and Museum Commission Colour: blue Wikimedia: Flickr: Google Streetview OpenStreetMap