The work of Dorothy Crowfoot Hodgkin at the University of Oxford. In this building from 1956-1972 and at other times elsewhere in the Oxford Science Area, Professor Dorothy Crowfoot Hodgkin (1910-1994) OM FRS Nobel Laueate led pioneering work on the structure of antibiotics, vitamins and proteins, including pencillin, vitamin B12 and insulin, using X-ray diffraction techniques. Many methods for solving crystal structure were developed taking advantage of digital computers from the earliest days. The work provided a basis for much of present day molecular structure driven molecular biology and medicinal chemistry