Daniel Hale Williams (1856-1931). Here was boyhood home of the Black physician who pioneered successful heart surgery, 1893. Founded Provident Hospital, Chicago, 1891. Chief surgeon at Freedmen's Hospital, Washington, D.C., 1894-98. Charter member, College of Surgeons, 1913.

US 22 eastbound (Blair St., 300 block), Hollidaysburg, PA, United States

Blair County. Formed on February 26, 1846 from Bedford and Huntingdon counties. Named for the Hon. John Blair, a prominent citizen who died in 1832. Hollidaysburg, county seat, was incorporated 1836. City of Altoona, founded 1849, became a major railroad center.

Courthouse, 423 Allegheny St., Hollidaysburg, PA, United States

Frankstown. The site, prior to 1748, of a Delaware-Shawnee village called Assunepachla. Here the trader, Frank Stevens, had a fur post as early as 1734. The Kittanning Path led through here.

444 Old US 22 near Wm. Penn Hwy. intersection, Hollidaysburg, PA, United States

Canal Basin. Here at Hollidaysburg the 127-mile Juniata Division of the Pennsylvania Canal met the Allegheny Portage Railroad, which extended 36 miles west over the mountain to Johnstown. The Juniata Division was opened in 1832, the railroad in March 1834. Regarded as an engineering marvel, the railroad climbed 1398 feet in ten miles.

N Juniata St. (US 22) at Canal Basin Park, Hollidaysburg, PA, United States